An isotonic solution that is cytoprotective.
Ringer’s solution is a solution containing several salts – Sodium Chloride, Potassium Chloride, Calcium Chloride and Sodium Bicarbonate – dissolved in water.2
Ringer’s solution is specially formulated to create an isotonic solution relative to body fluids at a physiological pH. The buffering capacity of Ringer’s solution offers advantages over solutions such as normal saline and may offer benefits for maintaining an optimal pH at the wound surface.2 Ringer’s solution is regularly used for the maintenance of organ and tissues in vitro and for therapeutic purposes. Moreover, Ringer’s solution is cytoprotective1 so it cleanses the wound without damaging fibroblasts and myofibroblasts, key cells in the granulation and tissue remodelling phases.1,3
Patented Rinsing-Absorption Mechanism
From the hydro-responsive core of HydroClean® plus Ringer’s solution is donated to the wound environment. At the same time, bacteria and tissue debris-laden wound exudate are absorbed and retained within the polyacrylate core.2
This exchange occurs due to the higher affinity of the polyacrylate polymer for the proteins in wound exudate, compared with the Ringer’s solution salts.2This produces a continuous rinsing effect supporting effective wound bed preparation.2
Hydro-Responsive Wound Dressing vs.
standard wound dressing
 Buffa, E. et al. (1997). The effects of wound lavage solutions on canine fibroblasts: An in vitro study. Veterinary Surgery 26(6), pp. 460-466.
 Rippon, M. and Ousey, K. (2015). HydroClean® plus. Hydro-Responsive Wound Dressing (HRWD): Clinical and Scientific Monograph. Heywood: Paul Hartmann Ltd. ISBN 978-194478863-9.
 Courderot-Masuyer, C. et al. (2005). Study on the behaviour of healthy fibroblasts and venous ulcers after infection with Pseudomonoas aeruginosa and in the presence of HydroClean® active dressing. Journal des Plaies et Cicatrisations 51, pp. 3-7.